UNAIR KU

Kita bertemu lagi,

Akhirnya aku bisa menulis blog ini setelah satu semester terakhir

Banyak yang tanya "gimana ndo kuliah di Universitas Airlangga itu ?" rasanya tuh ada asin ada kecut dan berbagai rasa nano nano yang bisa ya Bisa bikin elu pusing kepalanya. Dan berubah hal yang saya tekankan di sini saya berkuliah di jurusan d3 kesehatan dan keselamatan kerja UniversitasAirlangga. Yang masih dibawah naungannya fakultas vokasi yang dulu merupakan bagian dari fakultas kesehatan masyarakat Universitas Airlangga. Ya gitu deh jurusan yang dimana dibentuk fakultas baru tidak punya tempat untuk bernaung selalu berpindah-pindah tempat facebook nomaden. Tapi saya tetap bangga menjadi bagian dari Universitas Airlangga karena bisa mendapatkan beberapa akses kesehatan, pendidikan, pengembangan diri dan berbagai hal lainnya. Bisa mengembangkan minat dan bakat masing-masing mahasiswa Universitas Airlangga ini. 

Lambat laun universitas Airlangga menjadi universitas rujukan nasional maupun internasional Semoga bisa menjadikan sebuah 10 kampus terbaik di Indonesia. Ngomong-ngomong sebelum bahas indonesian surabaya sendiri memiliki kampus termegah dan terbaik seantero di timur Jawa Dwipa. Yaitu universitas Airlangga yang ber almamater berwarna biru kuning dan memiliki logo Prabu Airlangga yang membawa gentong kahuripan yang mengartikan bahwasanya tentang itu mengandung air kahuripan yang teman atau refund itu adalah air ilmu yang bisa mencerdaskan anak bangsa indonesia. 

Banyak alumni kita yang bisa menjadi orang-orang top. Ada yang jadi menteri ada yang menjadi artis atau menjadi pengusaha ataupun menjadi profesional di masing-masing bit mereka tekuni hingga saat ini aku ini tidak memiliki sangkut pautnya dengan pembahasan topik yang diatas ya mungkin saya awal sebagai penulis blog Jadi mohon dimaklumi Bagaimana cara penulisan saya agak agak salah. Mungkin step pertama sih saya bisa menulis ini dengan saya tapi tenang saya terhadap Universitas Airlangga ini. Pernyataan Saya mencintai universitas Airlangga ini ini. Banyak hal ya saya catat selama perkuliahan ini pengalaman organisasi pengalaman Bagaimana manajemen konflik teman-teman saya. Namun bagaimana cara bagaimanapun saya tetap mencintai Universitas Airlangga ini karena bisa mengembangkan bakat saya menjadi insan yang lebih baik dengan begitu saya bisa menjadikan keluaran output dari mahasiswa universitas airlangga ini menjadikan insan yang mulia atau dan makmur.

Study on crystallinity and compactibility of binary mixture of analgesic substances with Microcrystalline cellulose  

Setyawan, D. ,

Widjaja, B.,

Sari, R.

Department of Pharmaceutics, Airlangga University, Surabaya, Indonesia 

Abstract

Objectives: The aim of this study was to investigate crystallinity and compatibility transformation of two binary mixtures of analgesic substance with excipient due to mixing and compression. Methods: Analgesic substances used in this study were mefenamic acid (MA) and acetaminophen (AC). Each substance was mixed with microcrystalline selolusa as excipient with drug-excipient ratio of 70:30, 80:20 and 90:10 %w/w then compressed with pressure of 29.4 kN. Characterization was done by Powder X-Ray Diffraction (PXRD), thermal analysis (DTA), FTIR spectrometer and a Scanning Electron Microscope (SEM). Mechanical properties was also evaluated by calculating its tensile strength Results: Evaluation of crystallites size of MA and MA-MCC mixture showed that the value of MA crystallite size is relatively fixed in all the peaks observed. Crystallite size of the AC and AC-MCC mixture also showed similar results with MA. From the elastic modulus curve, it was recognized that the tensile strength of MA is greater than AC, it indicates that the MA is more plastic than AC. Conclution: X-ray powder diffraction of binary mixture indicated that intensity of both MA and AC decreased with increasing amount of MCC. The average crystallite size were 15-19 Å (MA) and 21-30 Å (AC). It was known that MA has compactibility better than AC.

Full Text :

https://www.researchgate.net/publication/259914035_Study_on_crystallinity_and_compactibility_of_binary_mixture_of_analgesic_substances_with_Microcrystalline_cellulose

Primary structure and intercellular space formation of feeding root in Sonneratia alba J. Smith

Purnobasuki, H.

Department of Biology, Airlangga University, J1 Mulyorejo (Kampus C Unair), Surabaya-60115, Indonesia 

Abstract

The aim of this research was to know the primary structure and intercellular space formation of feeding root in Sonneratia alba in order to relate their development and structure of their function as environmental adaptation in mangrove's root. The conventional histological techniques by Light Microscopy (LM) were used to get anatomical datas. This root has no cork covering. Cells of the meristem normally had dense cytoplasm and clear nucleus. Protoderm first appeared as a distinct layer at the edge of the tiers of cortical meristem. Root caps of feeding root of S. alba consist of two regions, i.e., weakly stained central columella or statenchyma and well-stained peripheral regions. The columella has 8-11 layers. The size of gas spaces is 100-320 μm. All the cells in the cortex appear round in cross section. Between 0-500 μm distances from the tip, few intercellular spaces and cortical cells are tightly packed. At distance more than 500 μm from the tip, cortical cells began to separate each other and resulted in the intercellular spaces between longitudinal files of the cortical cells. Changes of cortex cells with developing gas spaces suggested that cell separation (schizogenous) and enlargement of intercellular spaces has occurred to form aerenchyma in these plants. From its shape, structure and location, it seems clear that the primary structures of root assists the root in penetrating the soil and absorbs nutrient. The present study revealed that these plants have developed the structural adaptation in their roots as adaptation to their anaerobic habitat. © 2013 Asian Network for Scientific Information.

Full Text : 

http://www.scialert.net/abstract/?doi=ijb.2013.44.49

Activities of heterogeneous acid-base catalysts for fragrances synthesis: A review

Hartati, H.^abc,

Santoso, M.^b,

Triwahyono, S.^c,

Prasetyoko, D.^bd 

^a  Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya,60115,Indonesia
^b  Department of Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia 

Abstract

This paper reviews various types of heterogeneous acid-base catalysts for fragrances preparation. Catalytic activities of the various types of heterogeneous acid and base catalysts in fragrances preparation, i.e. non-zeolitic, zeolitic, and mesoporous molecular sieves, have been reported. Generally, heterogeneous acid cata-lysts are more commonly used in fragrance synthesis as compared to heterogeneous base catalysts. Heteropoly acids and hydrotalcites type catalysts are widely used as heterogeneous acid and base catalysts, respectively. © 2013 BCREC UNDIP.

Full Text :

http://ejournal.undip.ac.id/index.php/bcrec/article/view/4394

Development of piroxicam orally disintegrating tablets by freeze drying method

Widjaja, B.^a ,

Setyawan, D.^a,

Moechtar, J.^b

^a  Department of Pharmaceutics, Airlangga University, Indonesia ^b  

Abstract

Objective: the aim of this research was to optimize piroxicam orally disintegrating tablets (ODT) formulation by freeze drying method. Method: optimization was done by a 2² factorial design to observe the effect of gelatin as binder with levels of 1% and 2%, and ECG 505 as disintegrant with levels of 2.5% and 7.5%. The filler used was mannitol which also serves as sweetener. The mixture was suspended, filled into blisters and freeze dried. The physical characteristics of the resulting tablets were evaluated including hardness, friability, disintegration time and dissolution. Internal microstructures of the tablets were analyzed by Scanning Electron Microscope (SEM). Results: Increasing level of gelatin from 1% to 2% increased the tablet hardness, lowered the tablet friability and increased the tablet disintegration time. Increasing levels of gelatin from 1% to 2% showed a greater influence than of ECG 505 on the tablet disintegration time, while increasing levels of ECG 505 from 2.5% to 7.5% showed a greater influence on the amount of piroxicam dissolved than of gelatin. Conclusion: evaluation of tablets physical quality showed that within the "feasible area" of the design space, the tablets met the specifications of hardness, disintegration time and % piroxicam dissolved but did not meet the friability specification. The SEM photomicrographs showed that the tablets have a porous structure.

Full Text :

https://www.researchgate.net/publication/259913794_Development_of_piroxicam_orally_disintegrating_tablets_by_freeze_drying_method

Natural antioxidants in cosmetics

Kusumawati, I.,

Indrayanto, G.

Faculty of Pharmacy, Airlangga University, Dharmawangsa Dalam, Surabaya, Indonesia 

Abstract

Many cosmetics that are marketed nowadays often contain antioxidants as the active ingredients. It is known that oxidation reactions could produce free radicals, which can start chain reactions that will damage skin cells. Increasing the amount of free radicals could initiate the wrinkling, photoaging, elastosis, drying, and pigmentation of the skin. Topical antioxidants could terminate the chain reactions by removing the free radical intermediates and inhibit other oxidation reactions by being oxidized themselves; this could defend the skin against the environmental stress caused by free radicals. It is well known that plants can produce natural antioxidant compounds that could control the oxidative stress caused by sunlight and oxygen. Many patents and commercial cosmetic products have various combinations of plant extracts. The cosmetic formulations usually contain various combinations of many plant extracts, for example, green tea, rosemary, grape seed, basil grape, blueberry, tomato, acerola seed, pine bark, and milk thistle. These plants extracts contain natural antioxidants, that is, polyphenols, flavonoids, flavanols, stilbens, and terpenes (including carotenoids and essential oils). Some commercial products contain pure natural compounds such as quercetin, kojic acid, and resveratrol in their formulation. The choice of the right active plant extracts or compounds, the confirmation of their activity, and their stability and synergistic effects in cosmetic products are the important factors for the formulation of an effective product. © 2013 Elsevier B.V. All rights reserved.

Full Text :

http://www.sciencedirect.com/science/article/pii/B9780444596031000151